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Takashi Takahashi Selected Research

Receptor Tyrosine Kinase-like Orphan Receptors

11/2021Development of a DELFIA method to detect oncofetal antigen ROR1-positive exosomes.
3/2021Inhibition of heat shock protein 90 destabilizes receptor tyrosine kinase ROR1 in lung adenocarcinoma.
1/2019ROR1-CAVIN3 interaction required for caveolae-dependent endocytosis and pro-survival signaling in lung adenocarcinoma.
2/2016Receptor tyrosine kinase-like orphan receptor 1, a target of NKX2-1/TTF-1 lineage-survival oncogene, inhibits apoptosis signal-regulating kinase 1-mediated pro-apoptotic signaling in lung adenocarcinoma.
1/2016ROR1 sustains caveolae and survival signalling as a scaffold of cavin-1 and caveolin-1.

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Takashi Takahashi Research Topics

Disease

69Neoplasms (Cancer)
11/2021 - 04/2002
60Lung Neoplasms (Lung Cancer)
07/2021 - 01/2002
20Adenocarcinoma of Lung
03/2021 - 06/2002
19Adenocarcinoma
07/2021 - 06/2002
18Carcinogenesis
01/2022 - 01/2002
18Neoplasm Metastasis (Metastasis)
07/2021 - 01/2002
15Infections
01/2020 - 06/2003
11Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
07/2021 - 11/2003
10Myocarditis (Carditis)
12/2013 - 03/2004
7Mesothelioma
06/2020 - 03/2010
6Lymphatic Metastasis
10/2020 - 06/2002
6Heart Failure
05/2010 - 03/2004
5Pneumonia (Pneumonitis)
07/2022 - 08/2003
5Small Cell Lung Carcinoma (Small Cell Lung Cancer)
11/2010 - 04/2002
4Carcinoma (Carcinomatosis)
01/2020 - 11/2006
4Bacteremia
01/2020 - 12/2003
4Squamous Cell Carcinoma (Epidermoid Carcinoma)
11/2018 - 04/2004
4Breast Neoplasms (Breast Cancer)
07/2010 - 08/2003
4Body Weight (Weight, Body)
05/2010 - 01/2004
4Chronic Fatigue Syndrome (Myalgic Encephalomyelitis)
03/2010 - 01/2004
3Renal Cell Carcinoma (Grawitz Tumor)
01/2022 - 01/2012
3Malignant Mesothelioma
04/2020 - 11/2012
3Fibrosis (Cirrhosis)
04/2020 - 03/2008
3Stomach Neoplasms (Stomach Cancer)
04/2018 - 05/2004
3Colonic Neoplasms (Colon Cancer)
03/2018 - 04/2004
3Hemolysis
01/2017 - 02/2011
3Necrosis
12/2011 - 08/2004
3Pulmonary Fibrosis (Fibrosing Alveolitis)
06/2011 - 04/2007
3Asthma (Bronchial Asthma)
04/2011 - 07/2005
3Osteoporosis
01/2010 - 06/2008
3HIV Infections (HIV Infection)
08/2003 - 01/2002
2Meningitis
04/2021 - 06/2011
2Hypoxia (Hypoxemia)
11/2018 - 07/2008
2Disease Progression
07/2018 - 12/2013
2Diarrhea
05/2018 - 05/2004
2Alzheimer Disease (Alzheimer's Disease)
01/2017 - 10/2014

Drug/Important Bio-Agent (IBA)

16Proteins (Proteins, Gene)FDA Link
04/2021 - 05/2005
14MicroRNAs (MicroRNA)IBA
06/2020 - 06/2004
12Messenger RNA (mRNA)IBA
07/2021 - 08/2003
12Biological ProductsIBA
09/2014 - 10/2002
8AsbestosIBA
06/2020 - 03/2010
8ErbB Receptors (EGF Receptor)IBA
03/2012 - 10/2003
7Tyrosine Kinase InhibitorsIBA
09/2014 - 10/2003
7AdiponectinIBA
05/2010 - 08/2003
6IronIBA
01/2022 - 03/2010
6Transcription Factors (Transcription Factor)IBA
07/2021 - 06/2002
6Pharmaceutical PreparationsIBA
01/2014 - 08/2006
6Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
05/2010 - 11/2005
5Receptor Tyrosine Kinase-like Orphan ReceptorsIBA
11/2021 - 01/2016
5dihydroceramide desaturaseIBA
07/2021 - 01/2016
5DNA (Deoxyribonucleic Acid)IBA
09/2019 - 04/2002
5Biomarkers (Surrogate Marker)IBA
09/2014 - 01/2010
4Phosphotransferases (Kinase)IBA
03/2021 - 10/2003
4AntigensIBA
01/2020 - 10/2003
4Anti-Bacterial Agents (Antibiotics)IBA
12/2019 - 04/2010
4LigandsIBA
10/2016 - 10/2003
4matrigelIBA
01/2014 - 01/2002
4Cisplatin (Platino)FDA LinkGeneric
01/2013 - 05/2004
4Gefitinib (Iressa)FDA Link
03/2012 - 10/2003
3ferric nitrilotriacetateIBA
01/2022 - 01/2012
3MacrolidesIBA
01/2020 - 04/2010
3Anti-Infective Agents (Microbicides)IBA
07/2018 - 12/2012
3Amyloid (Amyloid Fibrils)IBA
01/2017 - 10/2014
3Vascular Endothelial Growth Factor CIBA
01/2014 - 06/2002
3Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
01/2014 - 06/2005
3Antineoplastic Agents (Antineoplastics)IBA
10/2013 - 07/2002
3Amiodarone (Amiodarona)FDA LinkGeneric
08/2013 - 03/2008
3Carboplatin (JM8)FDA LinkGeneric
03/2012 - 03/2002
3Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
07/2010 - 03/2002
3bu-zhong-yi-qi-tangIBA
06/2009 - 01/2004
3CytokinesIBA
07/2007 - 03/2004
3RNA (Ribonucleic Acid)IBA
04/2005 - 12/2004
2Monoclonal AntibodiesIBA
07/2022 - 10/2016
2Proteasome Endopeptidase Complex (Proteasome)IBA
03/2021 - 04/2011
2Heat-Shock Proteins (Heat-Shock Protein)IBA
03/2021 - 08/2003
2Zoledronic Acid (Zometa)FDA Link
11/2020 - 01/2009
2SphingolipidsIBA
10/2020 - 01/2016
2CeramidesIBA
10/2020 - 01/2016
2Saccharated Ferric Oxide (Venofer)FDA Link
06/2020 - 03/2010
2Serpentine Asbestos (Chrysotile)IBA
04/2020 - 11/2012
2EnzymesIBA
03/2020 - 01/2002
2NucleotidesIBA
03/2020 - 06/2003
2Crocidolite Asbestos (Blue Asbestos)IBA
03/2020 - 03/2010
2Laminin ReceptorsIBA
01/2020 - 01/2017
2FluoroquinolonesIBA
01/2020 - 02/2012
2ParaffinIBA
04/2018 - 07/2006
2epigallocatechin gallate (epigallocatechin-3-gallate)IBA
01/2017 - 10/2010
2Therapeutic UsesIBA
01/2017 - 03/2002
2tau Proteins (tau Protein)IBA
10/2016 - 10/2014
2Peptides (Polypeptides)IBA
10/2016 - 01/2013
2Liposomes (Liposome)IBA
01/2016 - 02/2012
2NeurotensinIBA
09/2014 - 09/2010
2Erlotinib Hydrochloride (CP 358,774)FDA Link
09/2014 - 03/2012

Therapy/Procedure

15Therapeutics
11/2020 - 07/2002
4Drug Therapy (Chemotherapy)
01/2017 - 04/2004
3Intraperitoneal Injections
04/2020 - 03/2010
3Adjuvant Chemotherapy
04/2018 - 04/2004
2Aftercare (After-Treatment)
07/2022 - 11/2008
2Injections
01/2022 - 01/2011
2Lymph Node Excision (Lymph Node Dissection)
01/2020 - 05/2004